An investigation of cholesterol pathways in castration-resistant prostate cancer : the role of scavenger receptor class B type I (SR-BI)

Background. Scavenger Receptor Class B Type I (SR-BI) facilitates influx of cholesterol to the cell from lipoproteins in the circulation. This influx of cholesterol is important for many cellular functions, including synthesis of androgens. Castration-resistant prostate cancer tumors are able to syn...

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Bibliographic Details
Main Author: Twiddy, Alexis
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/39383