Single channel properties of the slow cardiac potassium current, IKs

The slow potassium current, IKs, abbreviates the cardiac action potential by repolarizing the membrane to a resting state. Mutations in the pore-forming IKs subunit, KCNQ1, cause long QT syndrome type 1 (LQT1), which increases risk of fatal arrhythmia. Despite the physiological and clinical importa...

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Bibliographic Details
Main Author: Werry, Daniel
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/38968