Single channel properties of the slow cardiac potassium current, IKs
The slow potassium current, IKs, abbreviates the cardiac action potential by repolarizing the membrane to a resting state. Mutations in the pore-forming IKs subunit, KCNQ1, cause long QT syndrome type 1 (LQT1), which increases risk of fatal arrhythmia. Despite the physiological and clinical importa...
Main Author: | |
---|---|
Language: | English |
Published: |
University of British Columbia
2011
|
Online Access: | http://hdl.handle.net/2429/38968 |