Development and characterization of intravesical mucoadhesive nanoparticulate formulations of paclitaxel and docetaxel for postoperative chemotherapy in non-muscle-invasive bladder cancer

The present work describes the development, in vitro and in vivo evaluation of mucoadhesive nanoparticulate formulations of paclitaxel (PTX) and docetaxel (DTX) for intravesical bladder cancer therapy. The nanoparticles developed for PTX and DTX delivery consisted of hyperbranched polyglycerol (HP...

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Bibliographic Details
Main Author: Mugabe, Clement
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/37727