Novel function of coagulation factor Xa : conversion into a clot-dissolving cofactor
PLASMIN-MEDIATED CONVERSION OF FXa INTO A CLOT-DISSOLVING COFACTOR. Factor Xa (FXa) is an essential blood clotting enzyme. A previously identified FXa derivative, Xa33/13, is generated by two distinct cleavages by the clot-dissolving (fibrinolytic) enzyme, plasmin. FXa is first converted to FXaβ by...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/36854 |