Mixture models for analysing high throughput sequencing data
The goal of my thesis is to develop methods and software for analysing high-throughput sequencing data, emphasizing sonicated ChIP-seq. For this goal, we developed a few variants of mixture models for genome-wide profiling of transcription factor binding sites and nucleosome positions. Our methods h...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/35982 |