Immunostimulatory properties and mechanisms of action of encapsulated methylated cpg oligodeoxynucleotides
Immunostimulatory oligodeoxynucleotides (ODN) containing unmethylated CpG motifs are powerful stimulators of innate as well as adaptive immune responses, exerting their activity through the triggering of the endosomally localized TLR9 by a poorly understood mechanism. The immunopotency and broad ran...
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| Language: | en |
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University of British Columbia
2008
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| Online Access: | http://hdl.handle.net/2429/353 |