Regulation of APP processing and Aβ production by BACE1

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease among elderly people. The main symptoms of AD are memory loss and cognitive deficits. One of the hallmarks of AD is neuritic plaques in the brain. Amyloid β protein (Aβ), a peptide of 39–42 amino acids, forms the predominant co...

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Bibliographic Details
Main Author: Deng, Yu
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/33601