Transmembrane pH gradients in liposomes: drug-vesicle interactions and proton flux
This thesis examines the properties of large unilamellar lipid vesicles (LUVs) having transmembrane pH gradients (ΔpH). These pH gradients Induce proton movement across the membrane and can result in accumulation of amines into the vesicles. A major focus of the thesis is to develop a quantitativ...
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| Language: | English |
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2008
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| Online Access: | http://hdl.handle.net/2429/2945 |