Dystroglycan-dependent modulation of aquaporin-4 distribution : a new target to prevent brain edema

Dystroglycan-dependent modulation of aquaporin-4 distribution : a new target to prevent brain edema

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Aquaporin-4 (AQP4) constitutes the principal water channel in the brain and is mainly clustered at the perivascular astrocyte endfeet. This polarized distribution is of major importance because it enhances water fluxes thereby modulating brain swelling in different pathophysiological conditions. Evi...

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Bibliographic Details
Main Author:	Noel, Geoffroy Pierre Jean-Claude
Language:	English
Published:	University of British Columbia 2010
Online Access:	http://hdl.handle.net/2429/27296

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