Dystroglycan-dependent modulation of aquaporin-4 distribution : a new target to prevent brain edema
Aquaporin-4 (AQP4) constitutes the principal water channel in the brain and is mainly clustered at the perivascular astrocyte endfeet. This polarized distribution is of major importance because it enhances water fluxes thereby modulating brain swelling in different pathophysiological conditions. Evi...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/27296 |