Interleukin-10 inhibition of tumor necrosis factor alpha production in activated macrophages requires SHIP1 and Btk

Inflammation is a physiological process required for defense against pathogens and the repair of damaged tissues. However, excessive or improper inflammation can be detrimental and results in a number of diseases such as rheumatoid arthritis and inflammatory bowel disease. To prevent the negative...

Full description

Bibliographic Details
Main Author: Golds, Gary Brandhorst
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/26036