Bladder tissue distribution of paclitaxel and docetaxel from polymeric nanoparticles
Taxane based drugs are commonly used second-line adjuvant therapies for the treatment of superficial bladder cancer. However, the effectiveness of these drugs following intravesical instillation is limited, because of a short drug residence time and poor drug penetration into the bladder wall. The g...
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Language: | English |
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University of British Columbia
2010
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Online Access: | http://hdl.handle.net/2429/25406 |