Bladder tissue distribution of paclitaxel and docetaxel from polymeric nanoparticles

Taxane based drugs are commonly used second-line adjuvant therapies for the treatment of superficial bladder cancer. However, the effectiveness of these drugs following intravesical instillation is limited, because of a short drug residence time and poor drug penetration into the bladder wall. The g...

Full description

Bibliographic Details
Main Author: Tsallas, Antonia Theodora
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/25406