Bioactive marine natural products : isolation, structure elucidation and synthesis of pharmacophore analogues
Bioassay-guided fractionation of the marine sponge Spongia irregularis led to the isolation of a new sulfated sesterterpenoid, irregularasulfate (2.16), along with two known sulfated sesterterpenoids, halisulfate 7 (2.14) and hipposulfate C (2.15). All three compounds (2.14-2.16) inhibit the relate...
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Language: | English |
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University of British Columbia
2010
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Online Access: | http://hdl.handle.net/2429/23166 |