SPARC enhances chemosensitivity by activating the extrinsic pathway of apoptosis

Colorectal cancer (CRC) is the second leading cause of cancer death in Canada. Treatment failure in advanced disease is due to the development of chemotherapy resistance. Using a genomics approach, the Tai laboratory previously found that Secreted Protein Acidic and Rich in Cysteine (SPARC), a ma...

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Bibliographic Details
Main Author: Tang, Michelle Jocelyn
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/16685