Coxsackievirus B3 proteases 2A and 3C induce apoptotic cell death through a mitochondria-mediated pathway and cleavage of host factors for transcription and translation initiation

Coxsackievirus B3 (CVB3)-induced myocarditis is a common heart disease in children and young adults. This viral infection can cause severe cardiac injury and patients may experience progressive heart failure, which may ultimately lead to dilated cardiomyopathy (DCM). Since the development of viral m...

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Bibliographic Details
Main Author: Chau, David Hau Wing
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/15553