Crystallographic studies of bacterial proteins involved in β-lactam resistance

The β-lactams are an important class of antibiotics that target penicillin binding proteins (PBPs), bacterial enzymes that catalyze the final step of cell wall synthesis. The bacterial cell wall maintains cell shape and provides protection against osmotic lysis. PBPs catalyze the formation of pep...

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Bibliographic Details
Main Author: Lim, Daniel C.
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/15070