Molecular mechanisms of cellular activation

There is no biochemical evidence for the activation of Rac and Cdc42 in hemopoietic cells, nor is the mechanism of activation of these small GTPases well characterized in hemopoietic cells. We demonstrate here that lnterleukin-3 (IL-3) induced activation of endogenous Rac-1, Rac-2 and Cdc42. Rac-1 w...

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Bibliographic Details
Main Author: Grill, Brock
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/14968