Regulation of ATP-binding cassette transporter A1 in cholesteryl ester storage disease

Previous studies from the Francis laboratory have determined that regulation of ABCA1 expression is impaired in the lysosomal cholesterol storage disorder Niemann-Pick type C (NPC) disease, the presumed reason for the low plasma HDL-cholesterol (HDL-C) levels found in the majority of NPC disease pa...

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Bibliographic Details
Main Author: Bilbey, Nicolas James
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/14836