Regulation of muscle contraction by Troponin C
It is generally believed that calcium binding to Troponin C (TnC) in striated muscle acts as a simple switch, enabling tropomyosin to unblock myosin-binding sites on actin filaments. TnC has two domains, each containing a pair of structurally homologous sites. The high-affinity Ca2 +/Mg2 + bindin...
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| Language: | English |
| Published: |
2009
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| Online Access: | http://hdl.handle.net/2429/14768 |