Enzymatic properties of hepatitis C virus NS3 serine protease and bio-engineering of serine protease inhibitors (serpins) against the NS3 protease and elastase
Hepatitis C virus (HCV) has infected millions of people worldwide and emerged as a global health crisis. HCV NS3 serine protease domain (aa:1027-1218) of the HCV polyprotein, is required for the processing and maturation of the HCV viral non-structural (NS) proteins. As an essential protease for vir...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/14043 |