A synthetic approach to the variecolin class of sesterterpenoids : total syntheses of (+-)-5-deoxovariecolin, (+-)-5-deoxyvariecolol and (+-)-5-deoxyvariecolactone. A new cyclopheptenone annulation method employing the bifunctional reagent (Z)-5-iodo-1-tributylstannylpent-1-ene

The syntheses of three structurally related substances, (±)-5-deoxovariecolin (204), (±)-5-deoxyvariecolol (93) and (±)-5-deoxyvariecolactone (226) are described as part of a general synthetic strategy toward the variecolin class of sesterterpenoids (48-52). Thus, the known Grignard reagent 99 wa...

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Bibliographic Details
Main Author: Walker, Shawn Duane
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/13615

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