A synthetic approach to the variecolin class of sesterterpenoids : total syntheses of (+-)-5-deoxovariecolin, (+-)-5-deoxyvariecolol and (+-)-5-deoxyvariecolactone. A new cyclopheptenone annulation method employing the bifunctional reagent (Z)-5-iodo-1-tributylstannylpent-1-ene
The syntheses of three structurally related substances, (±)-5-deoxovariecolin (204), (±)-5-deoxyvariecolol (93) and (±)-5-deoxyvariecolactone (226) are described as part of a general synthetic strategy toward the variecolin class of sesterterpenoids (48-52). Thus, the known Grignard reagent 99 wa...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2009
|
| Online Access: | http://hdl.handle.net/2429/13615 |