In vivo characterization of the lysine-methyltransferases Set7/9 and G9a by conditional mutagenesis in the mouse

Increasing evidence suggests that site-specific lysine methylation of histone and non-histone proteins is fundamentally involved in epigenetic regulation of gene expression during cellular differentiation and tumorigenesis. To study the in vivo relevance of the lysine methyltransferases Set7/9 and G...

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Bibliographic Details
Main Author: Lehnertz, Bernhard
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/13027