Variable X inactivation of the human TIMP1 gene

X inactivation silences most of the genes on one of the two X chromosomes in mammalian females, presumably to achieve dosage compensation of X-linked gene products. The human X chromosome preserves its activation status when isolated in rodent/human somatic cell hybrids. Surprisingly, the human t...

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Bibliographic Details
Main Author: Anderson, Catherine Linda
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/13003