Biochemical characterization of signaling pathways regulating cell survival

The granulocyte/macrophage colony stimulating factor (GM-CSF) exerts its antiapoptotic effects on hemopoietic cells by activating multiple cellular signaling pathways including the phosphatidylinositol 3'-OH kinase (PI3K) cell survival pathway and the Ras-Raf-MEK-ERK kinase cascade. I hypothesi...

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Bibliographic Details
Main Author: Schubert, Kathryn M
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/12720