Characterization of the C-terminal protein tyrosine phosphatase-like domain of CD45
CD45 is a transmembrane two-domain protein tyrosine phosphatase (PTP) essential for thymocyte development and B cell maturation. Its tyrosine phosphatase activity is required for efficient signal transduction initiated by lymphocyte antigen receptors. As with most transmembrane two-domain phosphata...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2009
|
| Online Access: | http://hdl.handle.net/2429/12717 |