The synthesis and characterization of new sulfoxide complexes of ruthenium and their potential as anti-cancer agents

Areas of hypoxia (low O₂ content) within malignant tumours are often resistant to radiotherapy and chemotherapy. Compounds that work in conjunction with radiation or alone are required to remove or define hypoxic areas. The complexes cis-RuCl₂(DMS̲O)₃(DMSO̲) (1) and cis-RuCl₂(TMS̲O)₄ (3) (the figure...

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Bibliographic Details
Main Author: Yapp, Donald Tshin Tsun
Language:English
Published: 2008
Online Access:http://hdl.handle.net/2429/1229