An investigation of the mechanism of UDP-glucose dehydrogenase

UDP-glucose dehydrogenase (UDPGluDH) is an NAD⁺-dependent enzyme that catalyzes the two-fold oxidation of UDP-glucose to UDP-glucuronic acid. This enzyme is interesting in that its single active site carries out two sequential oxidations, whereas the majority of NAD⁺ - dependent dehydrogenases ca...

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Bibliographic Details
Main Author: Penney, Lisa C.
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/12167