MSH6 is an obligate partner in mismatch repair mediated mutation surveillance : an in vivo study

The DNA mismatch repair (MMR) system is primarily responsible for purging newly synthesized DNA of errors incurred during semi-conservative replication. Lesion recognition is initially carried out by one of two heterodimeric protein complexes, MutSα or MutSβ While the former, comprised of MSH2 an...

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Bibliographic Details
Main Author: Mark, Sean Christian
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/12134