Synthesis of N-phenethylnorhydromorphone : a hydromorphone analogue
Since its clinical introduction in 1926, hydromorphone (7) has been used in the treatment of moderate to severe pain. Hydromorphone (7) is a semi-synthetic congener of morphine (1), and it has a relative analgesic potency of 5 to 1 compared to its parent compound 1. It has been shown from previo...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/11862 |