Studies of X-chromosome inactivation and the identification of the Xist gene in the insectivore Scapanus orarius
X-chromosome inactivation is the transcriptional silencing of one of the two X chromosomes in the mammalian female and is thought to be a means of dosage compensation. The inactive X chromosome is condensed, late replicating, hypoacetylated and hypermethylated at CpG islands. The silenced chromos...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/11838 |