The effects of lipoproteins on cyclosporine A toxicity and uptake in renal cells
Cyclosporine A (CSA) is an effective immunosuppressant, but side effects such as renal toxicity can limit its therapeutic use. The hydrophobicity of CSA results in significant association of the drug with lipoproteins in the blood. Lipid levels in patients undergoing CSA therapy are correlated wi...
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Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/10725 |