The effects of lipoproteins on cyclosporine A toxicity and uptake in renal cells

Cyclosporine A (CSA) is an effective immunosuppressant, but side effects such as renal toxicity can limit its therapeutic use. The hydrophobicity of CSA results in significant association of the drug with lipoproteins in the blood. Lipid levels in patients undergoing CSA therapy are correlated wi...

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Bibliographic Details
Main Author: Peteherych, Kathy Dawn
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10725