In vitro-in vivo investigation of the hepatic extraction of RSD1070: a novel antiarrhythmic compound
Purpose. The hepatic extraction of a novel antiarrhythmic, RSD1070, was investigated to test the hypothesis that its poor bioavailability observed in rats is due to high hepatic metabolism. Methods. The pharmacokinetics of RSD1070 was examined in rats (n=8) and its metabolism was investigated usi...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/10470 |