A kinetic model for the HCN2 ion channel
The focus of my investigation is the hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channel, also known as the pacemaker channel. There are four mammalian isoforms (HCN1-HCN4) that share about 60% sequence identity with each other, all activated by hyperpolarization of the membrane...
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| Language: | English |
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University of British Columbia
2013
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| Online Access: | http://hdl.handle.net/2429/44696 |