Specific residues and regions within the KH and S1 domains of PNPase that are important for RNA binding and autoregulation

The turnover of RNA is a critical process governing key aspects of cell growth, regulation, and survival. In particular, gene expression is largely mediated by the differential stabilities of mRNAs and their corresponding levels of translation. Polynucleotide phosphorylase (PNPase) is a phosphate-...

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Bibliographic Details
Main Author: Wong , Alexander Guanghua
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/43127