Mitochondrial genome variation in healthy aging

Mitochondria are thought to play a role in the aging process through their production of reactive oxygen species (ROS), and their regulation of cell fate via senescence and apoptosis. We hypothesize that genetic variation in the mitochondrial genome may explain a portion of the phenotypic variance i...

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Bibliographic Details
Main Author: Fornika, Daniel John
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/43107