The impact of CD45 on dendritic cell activation and tolerogenic response

Dendritic cells (DCs) are potent antigen presenting cells that orchestrate the immune system to mediate either a pro- or anti-inflammatory response, by provision of critical instructive signals to T cells. The leukocyte-specific tyrosine phosphatase CD45 can influence the immune response by its abil...

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Bibliographic Details
Main Author: Boyce, Guilaine
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/43101