Role of Mycobacterium tuberculosis protein tyrosine phosphatase A in the pathogenesis of tuberculosis

One of the main mechanisms by which the etiological agent of tuberculosis (TB), Mycobacterium tuberculosis (Mtb), survives in the host macrophage is by its capacity to arrest phagosome acidification and fusion with lysosomes. This Mtb feature is associated with phagosomal exclusion of the Vacuolar H...

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Bibliographic Details
Main Author: Wong, Dennis Dick-Hang
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/42331