Template-directed protein misfolding in neurodegenerative disease

Protein misfolding diseases represent a large burden to human health for which only symptomatic treatment is generally available. These diseases, such as Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, and the systemic amyloidoses, are characterized by conversion of globular, nativelyfolde...

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Bibliographic Details
Main Author: Guest, William Clay
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/41990

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