Template-directed protein misfolding in neurodegenerative disease
Protein misfolding diseases represent a large burden to human health for which only symptomatic treatment is generally available. These diseases, such as Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, and the systemic amyloidoses, are characterized by conversion of globular, nativelyfolde...
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Language: | English |
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University of British Columbia
2012
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Online Access: | http://hdl.handle.net/2429/41990 |