Proprotein convertases and serine protease inhibitors : developing novel indirect-acting antiviral strategies against hepatitis c virus
Hepatitis C virus (HCV) utilizes host lipids for every stage of its lifecycle. HCV hijacks host lipid droplets (LDs) to coordinate assembly through the host lipoprotein assembly pathway; this facilitates uptake into hepatocytes through the low density lipoprotein receptor (LDLR). Induction of host l...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/39818 |