IGF-1 activates c-Abl to regulate PTPα tyrosine phosphorylation and cell migration

Protein tyrosine phosphorylation is an important cellular mechanism that regulates intracellular signalling pathways to control many cellular activities, including proliferation, growth and differentiation. Tyrosine phosphorylation is a reversible process regulated by protein tyrosine kinases and pr...

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Bibliographic Details
Main Author: Khanna, Ranvikram Singh
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/35358