The role of filopodia in the formation of spine synapses

In the mammalian brain, excitatory (glutamatergic) synapses are mainly located on dendritic spines; bulbous protrusions enriched with F-actin. Dendritic filopodia are thin protrusions thought to be involved in the development of spines. However, limited evidence illustrating the emergence of spines...

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Bibliographic Details
Main Author: Arstikaitis, Pamela
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/32688