Ontogeny of hepatic drug metabolizing enzymes in sheep
Administration of therapeutic, supplemental and social drugs to the mother during pregnancy exposes the fetus to these medicines and their metabolites, which can cause defects in nervous, renal, cardiac and metabolic functions. Hepatic metabolic enzymes such as cytochrome P450 (CYP) 2A6, 2C19, 2D6 a...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/29395 |