Deactivation of the LPS antagonist eritoran by HDL-associated apolipoproteins
Background: Sepsis is a complex and life-threatening infection by gram-negative bacteria that is caused by the endotoxin lipopolysaccharide or LPS. Lipid A, the active moiety of LPS, exerts its effects through interaction with toll-like receptor 4 (TLR4), triggering a signalling cascade that results...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2010
|
| Online Access: | http://hdl.handle.net/2429/27100 |