Structural and functional characterization of the DAXX N-terminal helix bundle and SUMO interaction motifs

The Fas death-domain associated (DAXX) protein was first discovered as an intermediary of a FADD-independent apoptosis signaling pathway. However, subsequent studies have established it as an important player in both transcription and cell cycle regulation. In this thesis, the first structural chara...

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Bibliographic Details
Main Author: Escobar-Cabrera, Eric
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/25748