The role of talin in LFA-1 function in cell-mediated cytotoxicity
Natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) are effectors of cell-mediated cytotoxicity towards virally infected and tumourigenic cells. The integrin leukocyte function associated antigen-1 (LFA-1) is required for the adhesion of effector cells to their targets. In addition, LFA-1 t...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/23244 |