High resolution optical tweezers for single molecule studies of hierarchical folding in the pbuE riboswitch aptamer
Riboswitches are gene regulatory elements found in messenger RNA that function by changing structure upon the binding of a ligand to an aptamer domain. Single adenine-binding pbuE riboswitch aptamer RNAs were unfolded and refolded co-transcriptionally using optical tweezers for single molecule force...
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| Format: | Others |
| Language: | en |
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2009
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| Online Access: | http://hdl.handle.net/10048/861 |