Functional characterization of class I Arfs and their Guanine Nucleotide Exchange Factors at the Golgi complex

We examined the function of ADP-ribosylation factors (Arfs) and their guanine nucleotide exchange factors (GEFs) that regulate recruitment of coat proteins on the Golgi complex. The large ArfGEF GBF1 localizes at the cis-Golgi complex while BIG1 and BIG2 localize at the trans-Golgi network (TGN)....

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Bibliographic Details
Main Author: Manolea, Florin Iulian
Other Authors: Dr. Paul Melanon (Department of Cell Biology)
Format: Others
Language:en
Published: 2009
Subjects:
TGN
Online Access:http://hdl.handle.net/10048/752