Characterization of a newly identified kidney Anion Exchanger 1 mutant, C479W
Anion Exchanger 1, AE1, is a membrane glycoprotein that functions as a dimer in the red blood cells (RBC) as well the kidney. It functions to exchange Cl- for HCO3- in an electroneutral manner, with the RBC AE1 having an additional function in maintaining its biconcave shape. Mutations in AE1 can...
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Format: | Others |
Language: | en |
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2010
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Online Access: | http://hdl.handle.net/10048/1035 |