Characterization of a newly identified kidney Anion Exchanger 1 mutant, C479W

Anion Exchanger 1, AE1, is a membrane glycoprotein that functions as a dimer in the red blood cells (RBC) as well the kidney. It functions to exchange Cl- for HCO3- in an electroneutral manner, with the RBC AE1 having an additional function in maintaining its biconcave shape. Mutations in AE1 can...

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Bibliographic Details
Main Author: Woods, Naomi
Other Authors: Cordat, Emmanuelle (Physiology)
Format: Others
Language:en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10048/1035